The splodgy stuff is a bit later than my interest, Keith, and I've not seen a square Mtarfa before, but given Mtarfa was set up by Paul Said, Joseph Said's brother, and they both trained at Mdina as MH's apprentices, I would imagine that in general, this style was started at Mdina and continued at Mtarfa, but I would still have no idea which of these two came first - I don't know how long this style was made at Mdina.
Does your big cloudy ambery bottle have a round ground pontil mark? It certainly looks like early (as in Harris/Boffo) period to me.
I have a large bottle like this, with a huge stopper, in blues and yellows, also some smaller, tall bottle decanters in this cloudy style, and another bottle in Earthtones, in a particular style of the design, many of which come with round ground pontil makrs, and while i have no official confirmation, I strpngly suspect they mught be Boffo. I also have a small round vase in the same colours as your bottle, with a similar patern in it to this unusual Earthtones design, but with the remnants of an old Mdina sticker on it. I'm convinced it's Mdina. An early bit.
Always happy to help!