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A very odd one. Everything from the top of the leaves down could be modern Chinese (a bit of emery paper can soon put wear on a base!). But the millefiori canes used for the flowers remind me a little of some in a paperweight I own, whose maker remains unknown. My best guess for the canes is 'European, probably pre-1950' - but that does not mean the whole weight is the same age as the millefiori canes, of course: bits of cane can sit on a shelf for many, many years before being used. In what country did you get it?
Alan